منابع مشابه
Non-paraneoplastic limbic encephalitis associated with NMDAR and VGKC antibodies.
INTRODUCTION Limbic encephalitis (LE) is characterised by seizures and impairment of short-term memory as well as behavioural and psychiatric symptoms such as anxiety, depression, personality change and hallucinations. Onset of these symptoms is typically subacute over a few weeks or months but may also evolve over a few days. In many patients, limbic encephalitis is a paraneoplastic syndrome u...
متن کاملFocal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis
Magnetic resonance imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-mediated limbic encephalitis with generalized hippocampal atrophy. However, autoantibodies bind to specific rodent hippocampal subfields. Here, human hippocampal subfield (subiculum, cornu ammonis 1-3, and dentate gyrus) targets of immunomodulation-treated LGI1 VGKC-complex antibody-mediated li...
متن کاملDelayed LGI1 seropositivity in voltage-gated potassium channel (VGKC)-complex antibody limbic encephalitis
We utilise a clinical case to highlight why exclusion of voltage-gated potassium channel (VGKC)-complex autoantibody testing in serological evaluation of patients may delay or miss the diagnosis. A 68-year-old man presented with increasing involuntary movements consistent with faciobrachial dystonic seizures (FBDS). Initial evaluation demonstrated VGKC antibody seropositivity with leucine-rich ...
متن کاملAutoimmune limbic encephalitis due to VGKC-Ab. Thanks for the memory. Leo Robin (Title of song, 1937).
To cite: Morrow J. Pract Neurol 2016;16:162–165. With the benefit of hindsight, I had probably been unwell for weeks or even months before the worsening of my condition was sufficient for me to allow my wife to finally seek medical advice on my behalf. I can therefore really only directly relate parts of my acute illness as I retain sketchy recollections of this time, so my wife (Sue) has fille...
متن کاملCase Series Case Series
30 SAJR March 2013 Vol. 17 No. 1 Primary bone tumours account for 5% of all adolescent and child cancers. The Ewing’s sarcoma family of tumours is an aggressive form of childhood cancer and comprises the second most common primary bone tumour that includes Ewing’s sarcoma, Askin’s tumour and peripheral primitive neuro-ectodermal tumour (PNET). When Ewing’s sarcoma arises in soft tissue (25%) ra...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2014
ISSN: 0022-3050,1468-330X
DOI: 10.1136/jnnp-2014-309236.16